Journal Club

2013


De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock

09.12.13 (D. Fasel)
J. Garnacho-Montero et al: De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock Intensive Care Med Sep 12 32-40 2013

Considerations for Higher Doses of Daptomycin in Critically Ill Patients With Methicillin- Resistant Staphylococcus aureus Bacteremia

02.12.2013 (Bernardini Claudia)
Falcone M. et al.: Considerations for Higher Doses of Daptomycin in Critically Ill Patients With Methicillin- Resistant Staphylococcus aureus Bacteremia CID 57(11): 1568–76 2013

High Morbidity and Mortality in Adults Hospitalized for Respiratory Syncytial Virus Infections

25.11.2013 (Esther Künzli)
Lee N. et al.: High Morbidity and Mortality in Adults Hospitalized for Respiratory Syncytial Virus Infections CID 57 1069-1077 2013

Dolutegravir plus Abacavir-Lamivudine for Treatment of HIV-1 Infection

11.11.13 (Mario Kurz)
Sharon L Walmsley: Dolutegravir plus Abacavir-Lamivudine for Treatment of HIV-1 Infection N Engl J Med 369 1807-1818 2013

Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes

04.11.2013 (Hanni Bartels)
Pasipanodya Jotam G. et al.: Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes J Infect Dis. 208 (9) 1464-1473 2013

Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery

21.10.2013 (Botond Lakatos)
Fowler GV et al.:Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery JAMA 309 1368-1378

Virologic failure following persistent low-level viremia in a cohort of HIV-positive patients: results from 12 years of observation

14.10.2013 (Michael Osthoff)
Laprise C et al.: Virologic failure following persistent low-level viremia in a cohort of HIV-positive patients: results from 12 years of observation Clin Infect Dis Advances access publication September 6, 2013 1-8 2013

Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing

07.10.2013 (Adrian Schibli) David W. Eyre et al.: Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing NEJM 369 1195-1205 2013

High Levels of Hepatitis B Virus After the Onset of Disease Lead to Chronic Infection in Patients with Acute Hepatitis B

30.09.13 (Barbara Jakopp) Yotsuyanagi H. et al.: High Levels of Hepatitis B Virus After the Onset of Disease Lead to Chronic Infection in Patients with Acute Hepatitis B CID 2013:57 935-942 2013

Impact of matrix-assisted laser desorption ionization time-of-flight mass spectrometry on the clinical management of patients with Gram-negative bacteremia: a prospective observational study

16.09.13 (Sarah Tschudin Sutter)
Clerc O et al.: Impact of matrix-assisted laser desorption ionization time-of-flight mass spectrometry on the clinical management of patients with Gram-negative bacteremia: a prospective observational study.
Clin Infect Dis 56 1101-7 2013

The Use of Cefepime for Treating AmpC ß -Lactamase-Producing Enterobacteriaceae

09.09.2013 (Mario Kurz)
Tamma et al.: The Use of Cefepime for Treating AmpC  ß -Lactamase-Producing Enterobacteriaceae
CID 57 781-788

Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial

02.09.2013 (Danielle Vuichard)
Farrar J. et al. for the South East Asia Infectious Disease Clinical Research Network: Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial
BMJ 346 1-16 2013

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components

26.08.2013 (Hanni Bartels)
Neagu, M. R. et al.: Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
J. Clin. Invest. Volume 119, Issue 10 3035–3047 2009

Lymphogranuloma Venereum in Men Screened for Pharyngeal and Rectal Infection, Germany

19.8.2013 (Daniel Goldenberger)
Haar K. et al.: Lymphogranuloma Venereum in Men Screened for Pharyngeal and Rectal Infection, Germany
Emerg Infect Dis 19 488-492 2013

A risk for Hepatocellular Carcinoma persists long-term after sustained virologic response in patients with Hepatitis C-associated liver cirrhosis

12.08.2013 (Esther Künzli)
Aleman S. et al.: A risk for Hepatocellular Carcinoma persists long-term after sustained virologic response in patients with Hepatitis C-associated liver cirrhosis
CID 57 230-236 2013

Dolutegravir versus raltegravir in antiretroviral-experienced integrase-inhibitor-naive adults with HIV: week 48 results from the randomised, double-blind, non-inferiority SAILING study

5.08.13 (Luigia Elzi)
Cahn P. et al.: Dolutegravir versus raltegravir in antiretroviral-experienced integrase-inhibitor-naive adults with HIV: week 48 results from the randomised, double-blind, non-inferiority SAILING study
Lancet Published online 3 July 2013 2013

Natural Selection in a Bangladesi Population from the Cholera-Endemic Ganges River Delta

29.07.2013 (Adrian Egli)
Elinor K. Karlsson: Natural Selection in a Bangladesi Population from the Cholera-Endemic Ganges River Delta
Science Translational Medicine 5 192ra86 p1-11 2013

Community-associated Clostridium difficile infection and antibiotics: a meta-analysis

22.07.13 (D.Fasel)
Abhishek Deshpande, Vinay Pasupuleti et al: Community-associated Clostridium difficile infection and antibiotics: a meta-analysis
Journal of Antimicrobial Chemotherapy, April 25, 2013 April 25, 2013 1-11 2013

U.S. Hospitalizations for Pneumonia after a Decade of Pneumococcal Vaccination

15.07.2013 (Marcel Stöckle)
Griffin M.R.: U.S. Hospitalizations for Pneumonia after a Decade of Pneumococcal Vaccination
New Engl J Med 369 155-63 2013

The Immunomodulatory Nutritional Intervention NR100157 Reduced CD4+ T-Cell Decline and Immune Activation: A 1-Year Multicenter Randomized Controlled Double-Blind Trial in HIV-Infected Persons Not Receiving Antiretroviral Therapy (The BITE Study)

08.07.2013 (Claudia Bernardini)
Cahn P. et al.: The Immunomodulatory Nutritional Intervention NR100157 Reduced CD4+ T-Cell Decline and Immune Activation: A 1-Year Multicenter Randomized Controlled Double-Blind Trial in HIV-Infected Persons Not Receiving Antiretroviral Therapy (The BITE Study)
Clin Infect Dis 57 139-146 2013

Effect of adequate single-drug vs combination antimicrobial therapy on mortality in Pseudomonas aeruginosa bloodstream infections: a post hoc analysis of a prospective cohort

01.07.2013 (Esther Künzli)
Pena C. et al.: Effect of adequate single-drug vs combination antimicrobial therapy on mortality in Pseudomonas aeruginosa bloodstream infections: a post hoc analysis of a prospective cohort
CID 57 208-216 2013

Effect of Daily Clorhexidine Bathing on Hospital-Acquired Infection

24.06.2013 (Botond Lakatos)
Climo Michael W. et al.: Effect of Daily Clorhexidine Bathing on Hospital-Acquired Infection
NEJM 368 533-542 2013

Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial

10.06.2013 (D. Fasel)
C. Orla Morrissey et al.: Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial
Lancet Infect Dis April 30, 2013, 13: 519–28 519-528 2013

Differentiation of Reinfection from Relapse in Recurrent Lyme Disease

03.06.2013 (Adrian Schibli)
R. Nadelman, G. Wormser et al.: Differentiation of Reinfection from Relapse in Recurrent Lyme Disease
NEJM 367:20 1883-1890

Test-and-Treat in Los Angeles: A Mathematical Model of the Effects of Test-and-Treat for the Population of Men Who Have Sex With Men in Los Angeles County

27.05.2013 (Miriam Luginbühl)
Sood N. et al.: Test-and-Treat in Los Angeles: A Mathematical Model of the Effects of Test-and-Treat for the Population of Men Who Have Sex With Men in Los Angeles County
CID 56 1789–96 2013

Urinary Tract Infection in Male Veterans, Treatment Patterns and Outcomes

13.05.2013 (Mario Kurz)
Dimitri M. Drekonja: Urinary Tract Infection in Male Veterans, Treatment Patterns and Outcomes
JAMA Intern Med 173(1):62-68 62-68 2013

Penicillin to prevent recurrent leg cellulitis

06.05.2013 (Andreas Widmer)
Thomas KS. et al.: Penicillin to prevent recurrent leg cellulitis
N Engl J Med 2;368(18) 1695-703

Association between colistin dose and microbiologic outcomes in patients with multidrug-resistant gram-negative bacteremia

22.04.2013 (Tobias Schön)
Vicari: Association between colistin dose and microbiologic outcomes in patients with multidrug-resistant gram-negative bacteremia.
Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am. 2013; 56:398–404 398-404 2013

Ampicillin Plus Ceftriaxone Is as Effective as Ampicillin Plus Gentamicin for Treating Enterococcus faecalis Infective Endocarditis

08.04.2013 (Reno Frei)
Fernández-Hidalgo N. et al.: Ampicillin Plus Ceftriaxone Is as Effective as Ampicillin Plus Gentamicin for Treating Enterococcus faecalis Infective Endocarditis
Clin Infect Dis 56 1261-8 2013

Near-universal prevalence of Pneumocystis and associated increase in mucus in the lungs of infants with sudden unexpected death

25.03.2013 (Tobias Schön)
Vargas et al 2013: Near-universal prevalence of Pneumocystis and associated increase in mucus in the lungs of infants with sudden unexpected death.
Clinical Infectious Diseases 2013, 56 (2): 171-179 2013

Comparative Effectiveness of Two Doses versus Three Doses of Hepatitis A Vaccine in HIV-infected and HIV-uninfected Men Who Have Sex with Men

18.03.2013 (Marcel Stöckle)
Yu-Tzu T.: Comparative Effectiveness of Two Doses versus Three Doses of Hepatitis A Vaccine in HIV-infected and HIV-uninfected Men Who Have Sex with Men
Hepatology Accepted article doi: 10.1002/hep.26210

Safety and Immunogenicity of 4 Intramuscular Double Doses and 4 Intradermal Low Doses vs Standard Hepatitis B Vaccine Regimen in Adults with HIV-1

11.03.2013 (Barbara Jakopp)
Odile Launay: Safety and Immunogenicity of 4 Intramuscular Double Doses and 4 Intradermal Low Doses vs Standard Hepatitis B Vaccine Regimen in Adults with HIV-1
JAMA 305 (14) 1432-1440 2011

Telephone Consultation Cannot Replace Bedside Infectious Disease Consultation in the Management of Staphylococcus aureus Bacteremia

04.03.2013 (Veronika Bättig)
Forsblom E. et al.: Telephone Consultation Cannot Replace Bedside Infectious Disease Consultation in the Management of Staphylococcus aureus Bacteremia
CID 56 527-35 2013

The Rise of Tropheryma whipplei : a 12-Year Retrospective Study of PCR Diagnoses in Our Reference Center

25.02.2013 (Daniel Goldenberger)
Edouard S et al.:The Rise of Tropheryma whipplei : a 12-Year Retrospective Study of PCR Diagnoses in Our Reference Center
J Clin Microbiol 50 3917-3920 2012

Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspectet: a 12-country, randomised, placebo-controlled trial

11.02.2013 (D.Fasel)
Paul Little et al: Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspectet: a 12-country, randomised, placebo-controlled trial
Lancet Infect Dis

Treatment with Neuraminidase Inhibitors for critically ill patients with Influenza A (H1N1) pdm09

04.02.2013 (Adrian Schibli)
Louie Janice K. et al: Treatment with Neuraminidase Inhibitors for critically ill patients with Influenza A (H1N1) pdm09
Clin Inf Dis 55 1198-1204 2012

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

28.01.2013 (Stefan Erb)
Els van Nood et al.: Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile
NEJM 1-7 2013

Epidemiology, clinical presentation, and antibody response to primary infection with Herpes simplex virus Type 1 and Type 2 in young women

21.01.2013 (Esther Künzli)
Bernstein DI et al.: Epidemiology, clinical presentation, and antibody response to primary infection with Herpes simplex virus Type 1 and Type 2 in young women
CID 56 344-51 2013

Continuous Infusion of Beta-Lactam Antibiotics in Severe Sepsis: A Multicenter Double-Blind, Randomized Controlled Trial

14.01.2013 (Nina Khanna)
Joel M. Dulhunty et al.: Continuous Infusion of Beta-Lactam Antibiotics in Severe Sepsis: A Multicenter Double-Blind, Randomized Controlled Trial
CID 56(2) 236-244 2013