Psychopharmacology Research Group

Prof Dr. Matthias Liechti, MD, MAS
Departement of Biomedicine
University Hospital Basel
Schanzenstrasse 55
CH-4056 Basel
Switzerland

Phone: +41 61 328 68 68

 

Research interests

  • Psychopharmacology
  • Pharmacokinetic and pharmacodynamic interactions of psychoactive drugs
  • Pharmacology of psychedelic substances
  • Pharmacogenetics
  • CNS drug development
  • Novel psychoactive substances
  • Pharmaco-fMRI
  • dose optimization and personalisation for psychotropi substances
 

Research projects

The group investigates the pharmacology of psychoactive substances both in vitro and in humans. The group is best known for the work on the acute effects psychoactive substances including MDMA (ecstasy), methylphenidate (Ritalin) and LSD in humans. In experimental clinical studies the group described the acute effects of psychoactive substances on social cognition (mood recognition, empathy, social behavior), endocrine responses, pharmacokinetics-pharmacodynamics, and pharmacogenetics. Pharmaco-fMRI studies are conducted in collaboration with the Psychiatric University Clinic. The team also characterizes the pharmacological profiles of the constantly emerging novel psychoactive substances (designer drugs) using in vitro methods in the laboratory at the Department of Biomedicine.

 

Head of the group

  • Prof. Dr. med. Matthias Liechti
 

Group members

  • Patrick Vizeli
  • Frederike Holze
  • Laura Ley
  • Anna Becker
  • Isabelle Straumann
  • Karolina Kolaczynska
  • Yasmin Schmid
 

Former group members

  • Patrick Dolder
  • Cédric Hysek
  • Linda Simmler
  • Anna Rickli
  • Dino Lüthi