2018
A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile–associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation | 17.12.2018 (Silvio Ragozzino) Mullane KM. et al.: A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile–associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation Clin Infect Dis. [Epub ahead of print] 2018 |
Effectivness of a group B outer membrane vesicle meningococcal vaccine against gonorhoea in New Zealand: a retrospective case-control study | 10.12.2018 (Marcel Stöckle) Petousis-Harris H. et al.: Effectivness of a group B outer membrane vesicle meningococcal vaccine against gonorhoea in New Zealand: a retrospective case-control study Lancet 390 1603-10 2017 |
Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis | 03.12.2018 (Aurélien Martinez) Freedman et al.: Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis NEJM 379 2015-2026 2018 |
Urine Antigen Detection as an Aid to Diagnose Invasive Aspergillosis | 26.11.2018 (Sarah Dräger) Kieren A. Marr: Urine Antigen Detection as an Aid to Diagnose Invasive Aspergillosis CID 67 1705-1711 2018 |
Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS | 19.11.2018 (Maja Weisser) Meintjes G: Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS NEJM 379 1915-1925 2018 |
Effect of Increased Daily Water Intake in Premenopausal Women With Recurrent Urinary Tract Infections: A Randomized Clinical Trial | 12.11.2018 (Milena Junker) Hooton T. et al: Effect of Increased Daily Water Intake in Premenopausal Women With Recurrent Urinary Tract Infections: A Randomized Clinical Trial JAMA Intern. Med. 178 1509-1515 2018 |
Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: a phase 2, randomised, double-blind, non-feriority trial | 05.11.2018 (Sylvain Meylan) Portsmouth S.: Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: a phase 2, randomised, double-blind, non-feriority trial Lancet Published online October 25 2018 1 -10 2018 |
Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial | 22.10.2018 (Andrea Büchler) Alam N. et al.: Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial Lancet Respir Med 6 40-50 2018 |
Phase 2b placebo-controlled trial of M72/AS01E candidate vaccine to prevent active tuberculosis in adults | 15.10.2018 (Kai-Manuel Adam) Olivier Van Der Meeren et al.: Phase 2b placebo-controlled trial of M72/AS01E candidate vaccine to prevent active tuberculosis in adults N Engl J Med. 379 1621-1634 2018 |
Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumonia Bloodstream Infection and Ceftriaxone Resistance | 08.10.2018 (Fabian Franzeck) Harris P et. Al.: Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumonia Bloodstream Infection and Ceftriaxone Resistance JAMA 320 984-94 2018 |
Development and Validation of a Prediction Model for Mortality and Adverse Outcomes Among Patients With Peripheral Eosinopenia on Admission for Clostridium difficile Infection | 24.09.2018 (Sylvain Meylan) Kulaylat A.S. et al.: Development and Validation of a Prediction Model for Mortality and Adverse Outcomes Among Patients With Peripheral Eosinopenia on Admission for Clostridium difficile Infection JAMA Surgery Ahead of publication E1-7 2018 |
Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis | 10.09.2018 (Sarah Dräger) Iversen, Kasper: Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis NEJM 10. DOI: 10.1056/NEJMoa1808312 1-10 2018 |
Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a stud | 27. 08.2018 (von Rotz Matthias) Llanos-Cuentas A. et al.: Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study Lancet Infect Dis 18: 874-83 2018 |
Outbreak of vancomycin-resistant Enterococcus faecium clone ST796, Switzerland, December 2017 to April 2018 | 20.08.2018 (Alexander Schweiger) Wassilew N. et al.: Outbreak of vancomycin-resistant Enterococcus faecium clone ST796, Switzerland, December 2017 to April 2018 Euro Surveill 23 pii=1800351 2018 |
Inactivated varicella zoster vaccine in autologous haemopoietic stem-cell transplant recipients: an international, multicentre, randomised, double-blind, placebo-controlled trial | 13.08.2018 (Aurélien Emmanuel Martinez) Winston D. et al.: Inactivated varicella zoster vaccine in autologous haemopoietic stem-cell transplant recipients: an international, multicentre, randomised, double-blind, placebo-controlled trial Lancet 391 2116-27 2018 |
Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults | 06.08.2018 (Niklaus Labhardt) Menzies D et al.: Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults NEJM 379 440-453 2018 |
Cap-Dependent Endonuclease Inhibitor S-033188 for theTreatment of Influenza: Results from a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study in Otherwise Healthy Adolescents and Adults with Seasonal Influenza | 16.07.2018 (Andrea Büchler) S. Portsmouth et al.: Cap-Dependent Endonuclease Inhibitor S-033188 for theTreatment of Influenza: Results from a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study in Otherwise Healthy Adolescents and Adults with Seasonal Influenza Oral Abstract Session, ID Week 2017 2017 |
Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse. | 09.07.2018 (Parham Sendi) Zegri-Reiriz I. et al.: Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse. J Am Coll Cardiol. 71 2731-2740 2018 |
Comparing the Outcomes of Adults With Enterobacteriaceae Bacteremia Receiving Short-Course Versus Prolonged-Course Antibiotic Therapy in a Multicenter, Propensity Score–Matched Cohort | 02.07.2018 (Kai-Manuel Adam) Darunee Chotiprasitsakul, et al.: Comparing the Outcomes of Adults With Enterobacteriaceae Bacteremia Receiving Short-Course Versus Prolonged-Course Antibiotic Therapy in a Multicenter, Propensity Score–Matched Cohort Clin Infect Dis. 6 172-177 2018 |
Long term survival, health, social functioning, and education in patients with European Lyme Neuroborreliosis: nationwide Population based cohort study | 25.06.2018 (Fabian Franzeck) Obel N. et al.: Long term survival, health, social functioning, and education in patients with European Lyme Neuroborreliosis: nationwide Population based cohort study BMJ 361 k1998 2018 |
Azole Resistance of Environmental and Clinical Aspergillus fumigatus Isolates from Switzerland | 11.06.2018 (Daniel Goldenberger) Riat A et al.: Azole Resistance of Environmental and Clinical Aspergillus fumigatus Isolates from Switzerland Antimicrob Agents Chemother 62 E02088-17 2018 |
A new class of synthetic retinoid antibiotics effective against bacterial persisters | 04.06.2018 (Sylvain Meylan) Wooseong K. et al.: A new class of synthetic retinoid antibiotics effective against bacterial persisters. Nature 556 103-107 2018 |
Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study | 28.05.2018 (Sarah Dräger) Angela Huttner: Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study Lancet Infect Diseases 18 1-11 S1473-3099(18)30165-8 2018 |
Acetaminophen as a renoprotective adjunctive treatment in patients with severe and moderately severe falciparum malaria: a randomized, controlled, open-label tria | 14.05.2018 (Marcel Stöckle) Plewes K. et al.: Acetaminophen as a renoprotective adjunctive treatment in patients with severe and moderately severe falciparum malaria: a randomized, controlled, open-label trial CID DOI: 10.1093/cid/ciy213 2018 |
Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women | 07.05.2018 (Reto Thoma) Huttner A, MD et al.: Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women JAMA 319(17) 1781-1789 2018 |
Comparison of dynamic monitoring strategies based on CD4 cell counts in virally suppressed, HIIV-positive individuals on combination antiretroviral therapy in high-income countries: a prospective, observational study | 16.04.2018 (Maja Weisser Rohacek) Caniglia EC: Comparison of dynamic monitoring strategies based on CD4 cell counts in virally suppressed, HIIV-positive individuals on combination antiretroviral therapy in high-income countries: a prospective, observational study Lancet HIV 4 E251-59 2017 |
Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial | 09.04.2018 (Aurélien Martinez) Molina J et al.: Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial Lancet infect dis 18 308–17 2018 |
26.03.2018 (Sylvain Meylan) Kaye K.S. et al.: Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection JAMA | |
Efficacy, safety, and tolerability of dolutegravir-rilpivirin for the maintenance of virological suppression in adults with HIV-1: phase 3, randomised, non-inferiority SWORD-1 and SWORD-2 studies | 12.03.2018 (A. Büchler) Llibre MJ et al.: Efficacy, safety, and tolerability of dolutegravir-rilpivirin for the maintenance of virological suppression in adults with HIV-1: phase 3, randomised, non-inferiority SWORD-1 and SWORD-2 studies Lancet http://dx.doi.org/10.1016/S0140-6736(17)33095-7 |
Trends in Pricing and Generic Competition Within the Oral Antibiotic Drug Market in the United States | 05.03.2018 (Sarah Dräger) Jonathan D. Alpern: Trends in Pricing and Generic Competition Within the Oral Antibiotic Drug Market in the United States CID 65 1848-52 2017 |
26.02.2018 (Niklaus D Labhardt) Mical P. et al.: Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial The Lancet Infectious diseases | |
Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis
| 12.02.2018 (Reto Thoma) P Schütz, Y Witz, R Sager, B Mueller: Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis The Lancet Infectious diseases, 18. January 95-107 2018 |
Within-host evolution of Enterococcus faecium during longitudinal carriage and transition to bloodstream infection in immunocompromised patients | 05.02.2018 (Seth-Smith, Helena) Moradigaravand D et al: Within-host evolution of Enterococcus faecium during longitudinal carriage and transition to bloodstream infection in immunocompromised patients Genome medicine 9 119 2017 |
Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial | 29.01.2018 (Veronika Bättig) Kronenberg A. et al.: Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial BMJ 359 j4784 2017 |
Depressive Symptoms in Patients Referred to a Tertiary Lyme Center: High Prevalence in Those Without Evidence of Lyme Borreliosis | 23.01.18 (Stefan Erb) Zomer PT et al: Depressive Symptoms in Patients Referred to a Tertiary Lyme Center: High Prevalence in Those Without Evidence of Lyme Borreliosis Clinical Infectious Diseases 65(10) 1689–94 2017 |
Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial | 15.01.2018 (Fabian Franzeck) Thwaites GE: Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial The Lancet Published online 2017 |
Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation | 08.01.2018 (L. Brockhaus) Marty F.M.: Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation NEJM December 6 DOI: 10.1056/NEJMoa1706640 2017 |